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In this study, in comparison with statin monotherapy, significantly more cases of infection, hyperglycaemia, new cases of diabetes mellitus, gastrointestinal or musculoskeletal symptoms, gastrointestinal bleeding, and skin symptoms were noted

Spotting or unscheduled bleeding between periods could also arise, which might cause some concern

J Cardiovasc Pharmacol 1992;20:157-64

Acknowledgements The authors would like to thank Neringa Zitkute and Sabrina Krarup for assisting with sample preparation

NK, natural killer