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Lv Q, Zhong Z, Hu B, Yan S, Yan Y, Zhang J, Shi T, Jiang L, Li W, Huang W (2021) MicroRNA-3473b regulates the expression of TREM2/ULK1 and inhibits autophagy in inflammatory pathogenesis of Parkinson disease

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Mice homozygous for the spontaneous ( Lepr db ) mutation develop severe obesity starting at 34 weeks of age, accompanied by overnutrition-related complications including postprandial hyperglycemia, and eventually pancreatic cell atrophy and hypoinsulinemia