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Les recherches prcliniques ont mis en vidence un large spectre d'activits biologiques, incluant la cytoprotection gastrique, la modulation de la voie de l'oxyde nitrique (NO) et l'interaction avec le systme dopaminergique

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Mol Med Rep (2018) 18(4):362530

General Safety Profile Based on the preclinical dataset and the limited human exposure data: No prominent signal of hepatic, renal, or hematological toxicity at tested doses No prominent cardiovascular safety flag Pregnancy and lactation as with most research compounds, safety not established Long-term effects not characterized What Clinicians Should Actually Tell Patients For patients asking about 5-amino-1MQ, a reasonable response framework: What the compound is: A research-stage small molecule inhibiting NNMT with promising preclinical fat loss data

[4] US Food and Drug Administration

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