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Nutrients 13(11):3812

This difference in action can influence their effectiveness and side effects

The patient should be maintaining adequate oral fluid intake without significant nausea or vomiting

This helped increase the release of GLP-1

Avoid excessive intake of alcohol and highly processed foods

At the same dose, a 74 kg participant had about 1.4 times the exposure of a 110 kg reference, while a 143 kg participant had about 0.8 times. Weight alone does not set the dose, but it helps explain why the trial mean transfers poorly to bodies outside the studied range