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Dysregulated iron metabolism not only promotes ferroptosis but also disrupts essential metabolic processes required for tissue repair, highlighting its role in ARDS progression ( 4.3 Fibrosis and long-term outcomes The chronic inflammation and unresolved ferroptosis associated with ARDS contribute significantly to lung fibrosis and long-term complications

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Conversely, upregulation of SLC39A14 in hepatocyte-specific TFR knockout mice leads to ferroptosis due to excess iron, making them more prone to liver fibrosis

RNA extraction Platypus and echidna tissues were obtained from adult animals in accordance with ethics guidelines (approved by Adelaide University Animal Ethics Committee permit AEC S-49200 to F.G)

In: SinghSKGulatiMMutalikSDhanasekaranMDuaK, editors

Have they always had a weight issue prior to having the mast cell activation challenge