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Reubi JC, Waser B

In addition, patients with PWS have a higher incidence of metabolic complications, such as CVD, T2D, hypertension, and obstructive sleep apnea [5, 14, 15], thus contributing to increased morbidity and mortality in these patients [14, 16]

Amino acids were used at concentrations of 3 mM based on previous work 11

This pattern may reflect genuinely selective effects on neural responses to the most energy-dense foods, or it may arise because responses to other food categories were near baseline levels, effectively washing out effects in the combined analysis

A recent analysis from Aon provides some promising data points to support this hypothesis

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