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Additionally, adequate and sustained glutathione levels are absolutely required to reverse the oxidative inhibition of the SHP-1 enzyme

It is a research concept explored in animal and in vitro work, not a proven clinical treatment

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Comparing REW with an engineered Fc variant with enhanced CDC activity, but without half-life extension 43,55 , equal CDC activity against a hard-to-kill cell line was measured for recombinant versions of anti-CD20 ofatumumab (SI Text 5, Fig

1 and 2)