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Two classes of agents have been developed to take advantage of the unique glucoregulatory potential of GLP-1: The incretin mimetics, such as exenatide (synthetic exendin-4, a peptide resistant to proteolytic cleavage by DPP-IV) or derivatives of GLP-1 (created by chemical modification of the native hormone, to render them resistant to rapid proteolytic cleavage by DPP-IV), targeting the pharmacological effects, and insufficient secretion of GLP-1 seen in type 2 diabetes

FOUNDAYO, by contrast, can be taken at any time of day, with or without food, with or without water

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Recent research shows that GLP-1 medications help lowerinflammation, leading to fewer flares, less joint pain and stiffness, better movement, and more energy

Treatment begins with an initial consultation