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This mechanism is hypothesised to contribute to the chronic and recurrent nature of NTHi-associated infections, including bronchitis, acute exacerbations of COPD, conjunctivitis, sinusitis, and OM (Kaya et al., 2013

They observed that etomoxir administration resulted in an increase in the mortality of aged but not adult ALI mice, thereby confirming that the CPT system is essential for survival from severe lung injury and indicating that adult mice have improved resilience to FAO inhibition

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