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Wegovy carries a separate cardiovascular indication for adults with established cardiovascular disease and either obesity or overweight, supported by a trial reporting a primary composite endpoint of 6.5% versus 8% with placebo, hazard ratio 0.80

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Another, authored by Professor Tim Spectorfounder of the ZOE diet app and nutrition expert based at King's College Londonrevealed those on high fibre diets produced less of a bile acid called isoUDC, which is linked to increased appetite

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