La dosis inicial suele ser de 0,25 mg
Adverse reactions are predominantly gastrointestinal, occur most commonly during dose initiation or escalation, and typically improve as patients adapt to each dose level [1]
Open-angle glaucoma is not a risk factor for angle closure glaucoma
Moreover, compelling evidence has linked MASLD to elevated risks of extrahepatic malignancies, including colorectal, breast, and pancreatic cancers, suggesting that hepatic steatosis and its metabolic milieu may exert carcinogenic effects beyond the liver 9
Maintenance schedule Month 1-2 : Stay at current dose, assess stability Month 3-4 : Reduce by 2.5mg, monitor weight Month 5-6 : Reduce again if weight stable Long-term : Minimum dose that prevents regain Coming off tirzepatide Not recommended : Abruptly stopping often leads to rapid weight regain
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