D-lactate is a secondary byproduct of the glyoxylate pathway and gut microbial metabolism, lacking mitochondrial oxidizing capacity in the central nervous system and undergoing non-enzymatic D-lactylation solely mediated by lactylglutathione (Xin et al., 2022
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Interestingly, the susceptibility of macrophages to ferroptosis varies significantly between the subtypes (82)
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Xiaofei Su, Nanjing First Hospital, China Updates Copyright 2022 Kim, Huh, Lee, Kang, Cha and Lee
Only proteins identified with at least two unique peptidesexcluding contaminants and reverse hitswere retained for downstream analysis