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Talk to Your Doctor Before You Indulge Most importantly, if youre on a GLP-1 medication and want a drink, discuss how much (if any) is safe for you with your doctor, says McTiernan

The full GI side effect spectrum Based on the meta-analysis data, here is how the major GI side effects compare across dose levels

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GLP-1 receptor agonists such as semaglutide have demonstrated robust efficacy in obesity research, while dual GLP-1/GIP agonists like tirzepatide have pushed those results further