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However, the findings and conclusions presented in this paper are those of the author(s) and do not necessarily reflect the views of the NIH or the U.S

This immune activation likely contributes to both pain and the fatigue and cognitive symptoms characteristic of the condition

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Suppression of SNAIL2, a zinc finger protein member of the SNAIL superfamily of epithelial-mesenchymal transition-inducing transcription factors (EMT-TFs) commonly overexpressed in pancreatic cancer patients, restored sensitivity of pancreatic cancer cell lines KLM1 and KMP5 to chemotherapy drug gemcitabine through an IGF binding protein 2 (IGFBP2)-dependent mechanism in vitro and in vivo (50)