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This effect helps reduce post-meal glucose spikes and contributes to increased satiety, often leading to reduced calorie intake and weight loss

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NHS access began in specialist weight management services from June 2025 for the highest-need patients, with tirzepatide prescribing incorporated into the GP Quality and Outcomes Framework from April 2026

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GGT catalyzes the transfer of a glutamyl residue (linked through glutamate gamma carboxylic acid to an amine or to another amino acid) to an acceptor, 102 thereby maintaining adequate levels of glutathione