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Weight loss from any method can include some lean mass loss, especially if calories are too low or protein and resistance training are inadequate
Starting dose considerations for specific populations Not everyone approaches the starting dose from the same position
The published research literature for Semaglutide includes large-scale outcome data in body composition models, cardiovascular outcome research (SUSTAIN and STEP trial series), renal function studies, and emerging neurological research examining GLP-1R agonism in Alzheimer's and Parkinson's disease models (the FLOW and EVOKE trial programmes)
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Hair thinning may reflect telogen effluvium from rapid weight loss or a direct drug effect, consistent with alopecia reported with licensed GLP-1 receptor agonists such as semaglutide
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