lixisenatide vs semaglutide Incretin-Based Therapies GLP-1 Receptor Agonists, Dual GIP/GLP-1 Agonists, Triple Agonists & Oral GLP-1 Therapies An overview of randomized clinical

Research consistently shows that successful long-term weight maintenance is challenging but achievable for some individuals with sustained effort

It was noted that the 3 studies involved samples which were not comparable, but which aided in the robustness of their analysis across different populations

PLoS One 7 (10), e47730 (2012) B

They have the genetic composition of several millions of people

The main differences across comparison categories are: Mechanism of Action: advantage goes to Semaglutide

Another possible explanation for the mixed results is that oxytocins effect on social behavior is limited when the treatment context lacks social cues