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In particular, increased plasma insulin concentrations stimulate the gonadotropin releasing hormone (GnRH) pulsatility and potentiate the LH-dependent effect on the ovarian theca cells, leading to the enhanced synthesis of androgens and to the arrest of pre-antral follicle development [13]

cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina) occurred in 109 participants

We found that pretreatment with GLP-1 (100 nM) increased intracellular cAMP accumulation in caSMCs compared with untreated controls (25.9 1.6 vs

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