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pinnata , quercetin and kaempferol, have been shown to increase the Bax/BCL-2 ratio, leading to depolarization of the mitochondrial membrane and, in osteosarcoma models, the activation of caspase-3/9 and the induction of apoptosis 35,36

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Proceedings of the National Academy of Sciences of the United States of America 99, 1604-1609CrossRefGoogle Scholar 125Beckman, J.S., Estvez, A.G., Crow, J.P

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