Altered expression of redox-responsive proteins and translocation of transcription factor NFB-p65, accompanied by activation of AMP-activated protein kinase (AMPK), SIRT-1, Glut-4, and PPAR- suggests the induction of antioxidant defense responses and increased energy metabolism in GK diabetic rats after exercise
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Increased export of GSH can be a part of GBM cells strategy to protect themselves from oxidative damage induced by this therapeutic approach, mitigating the harmful effects of ROS in the surrounding TME
Glutathione synthesis depends heavily on sulfur-containing amino acids, and those are far more concentrated in meat, fish and eggs than in most plant foods
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Data availability The mass spectrometry proteomics data have been deposited in the ProteomeXchange Consortium via the PRIDE (Perez-Riverol et al, 2025) partner repository with the dataset identifier PXD073941
