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This relationship is particularly significant given TMAOs association with cardiovascular diseases [24]

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The mouse MASH model was established using a high-fat diet combined with carbon tetrachloride (CCl 4 ) induction, and efficacy tests were conducted with both semaglutide and tirzepatide (Fig.4)

Additionally, it restored superoxide (O 2 ) formation, MDA levels, CAT activity, plasma NO metabolites, TNF-, and IL-6