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This step-up process matters because gastrointestinal side effects such as nausea, constipation, reflux, diarrhea, or reduced appetite can be more noticeable when the dose increases too quickly

[ref] How does a GLP-1 agonist work for weight loss By binding to the GLP-1 receptor, GLP-1 RAs mimic the effects of having eaten and released GLP-1

It may not suit people looking for a weight loss plan that focuses more on lifestyle changes, fitness, and nutrition

It is great for sharing with clients or using as a personal guide

Bruce Pynn is Oral Healths editorial board member for oral and maxillofacial surgery

Ethics declarations Competing interests R.Z.A