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Oral gavages are stressful, and there are likely differences in the uptake and metabolism between compounds administered orally (p.o.) and subcutaneously (s.c.), such as stimulation of gut hormones or altered first-pass metabolism

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Although the relationship between ASD and mitochondria is not new, the unique correlation varies across the different patients suffering from ASD, and an in-depth understanding of this correlation can help in better targeting of disease, and hence, the development of personalized mitochondrial therapy in ASD patients [191]