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"FoxO6 transcriptional activity is regulated by Thr26 and Ser184, independent of nucleo-cytoplasmic shuttling"

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For type 2 diabetes management, the medication may be needed long-term as diabetes is a chronic condition requiring ongoing treatment, though some patients may be able to reduce or discontinue medication if significant weight loss and lifestyle modifications lead to remission of their diabetes

The hype says "proven to heal" actual human evidence is three tiny pilot studies and zero controlled trials