Ultimately, Pfizer discontinued the entire program in April 2025, citing that the risk-benefit profile, including a potential case of drug-induced liver injury (DILI) in a recent study, did not support further development
Mol Cancer Ther
Each GLP-1RA has its advantages, and physicians have the flexibility to choose the appropriate drug according to the actual situation of the patient
Tornehave D, Kristensen P, Romer J, Knudsen LB, and Heller RS
Recent analyses have raised questions about psychiatric side effects, particularly mood changes and anxiety. Patients with asthma may be at increased risk of respiratory complications, and nutrient deficiencies can occur with long-term therapy. Monitoring mental health and nutritional status should be part of any GLP-1 program
Maintaining your weight loss after GLP-1 isnt about willpower, its about support, structure, and strategy