Maintain a consistent room temperature, avoiding exposure to direct sunlight, heat, or moisture as these can degrade the medication
Avoid freezing reconstituted solution as this damages peptide structure
A subsequent meta-analysis of trials (18 to 104 weeks duration) comparing a DPP-4 inhibitor (sitagliptin, saxagliptin, vildagliptin, linagliptin, alogliptin) with placebo (44 trials), a comparator from another class of antidiabetic agents (20 trials), or another DPP-4 inhibitor (three trials) showed a small increased risk of nasopharyngitis compared with placebo (6% vs
doi: 10.1210/jc.2014-3521 49 MaZChristiansenJSLaursenTLauritzenTFrystykJ
85 ZhangH.QiJ.WangY.SunJ.LiZ.SuiL.et al (2020)
Final Thoughts Oral tirzepatide drops are an emerging concept, not an established therapy