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IGF-1 is responsible for many of the downstream benefits of GH, including: Muscle protein synthesis Collagen production Tendon and joint repair Fat oxidation GHRP-2 increases circulating IGF-1 levels through stimulation of endogenous GH release, promoting anabolic and lipolytic effects. Arvat et al., Neuroendocrinology Summary: Why It Works So Well GHRP-2 triggers a physiological GH release pattern , with a pulsatile rhythm that is superior to the flat, non-pulsatile GH levels produced by MK-677 (MK-677 (Ibutamoren) Cycle) or synthetic HGH injections alone

*Correspondence: Karl J