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Vitamin-B7 or Biotin : It facilitates the metabolism of proteins and carbohydrates

It also has anti-inflammatory and anti-apoptotic properties by decreasing pro-inflammatory cytokines production including TNF- and IL-1 [308, 309]

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Pharmacokinetics (How Long They Last): Semaglutide: Half-life: Approximately 7 days Reaches steady state: After 4-5 weeks Duration of action: Remains active for one week between doses Time to peak concentration: 1-3 days after injection Tirzepatide: Half-life: Approximately 5 days Reaches steady state: After 4 weeks Duration of action: Remains active for one week between doses Time to peak concentration: 8-72 hours after injection Both medications are designed for once-weekly dosing and maintain therapeutic levels throughout the week

Zepbound's dual-action mechanism may explain why it often leads to more weight loss than Wegovy

10.1152/jappl.1992.73.5.2069 136 Murphree-TerryM.KeithJ