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Skin Aging Claims Versus Systemic Anti-Aging Claims Skin aging claims can point to topical studies on photoaging and wrinkle parameters, but systemic anti-aging claims often rely on gene expression, oxidative stress, inflammation, or animal data [2], [10], 17

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[16] [2] Anastrozole [edit] Anastrozole, brand name Arimidex, is a type of anti-estrogen used in treatment of breast cancer but is also used by bodybuilders to combat the estrogenic side effects associated with using anabolic steroids

De Candia et al., 2021)