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More recently, GLP-1 receptor agonists and GLP-1R/GIPR dual-agonists have been introduced as injectable therapies for T2D, which potentiates endogenous glucose-induced insulin secretion and slows gastric emptying for improved glycaemic control, as well as decreases appetite and food intake that consequently reduces body weight and further improves metabolic homeostasis

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synthesized two amphiphilic molecules mPEG-TK-DA and DTPA-N10-10 with ROS-scavenging functions, and self-assembled AGL through hydrophobic and hydrophilic interactions, forming multi-site ROS-scavenging nanoparticles called PDN@AGL

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