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This unique structure enables it to directly bind with free radicals, heavy metals (such as lead, mercury, arsenic), and toxins (such as mustard gas), playing a crucial role in detoxification
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Its main target is the stomach - to release ghrelin
The mice were randomly divided into four groups (each containing at least five mice): a natural aging group, a natural aging + FOXO4-DRI group, a D-Gal group, and a D-Gal + FOXO4-DRI group
At this stage, mitochondria-directed interventions [such as mitochondria-targeted coenzyme Q10 (MitoQ) and SkQ1] can still attenuate oxidative injury but may require combination strategies (iron chelation, GPX4 preservation and mitophagy rebalancing) to achieve structural benefits (35)