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In severe acute infections, this systemic consumption can completely drain the body's antioxidant reserves

(More information) High doses of supplemental -tocopherol may interfere with the vitamin K absorption and thus increase the risk of bleeding

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(5) B.Chen et al (2020) Combining MALDI mass spectrometry imaging and droplet-base surface sampling analysis for tissue distribution, metabolite profiling, and relative quantification of cyclic peptide melanotan II Analytica Chima Acta, 2020 Aug 15:1125:279-287