20% of body weight) are more likely to notice hair loss with GLP-1 RA usage.[ref] Studies note that this also occurs with other forms of weight loss, like bariatric surgery, and could be tied to reduced intake of nutrients such as protein, iron, biotin, or zinc
Some users also feel the price is high compared to basic fiber supplements
Alcohol considerations A common question for anyone starting GLP-1 treatment is whether you can drink alcohol on semaglutide or tirzepatide
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10.1038/s41392-024-01931-z Summary Keywords glucagon-like peptide-1 receptor, diabetes mellitus, -cell, insulin secretion, blood glucose Citation Li S, Huang N, Wang M, Huang W, Luo Y and Huang J (2025) GLP-1R in diabetes mellitus: from basic discovery to therapeutics development