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These decreases in body weight were not without costs, as semaglutide frequently caused gastrointestinal related side effects in patients

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Denifanstat for the treatment of metabolic dysfunction-associated steatohepatitis has been tested in a multicenter, double-blind, randomized, placebo-controlled Phase 2b trial conducted at 100 clinical sites in the U.S., Canada, and Poland, and the results of this Phase 2b trial support the advancement of denifanstat into Phase 3 development (145)

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