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Yan P, Wan Q, Zhang Z, et al

Minoxidil and finasteride, both approved in the 1980s and 1990s, offer modest and often temporary benefits, require lifelong use, and are associated with tolerability or safety concerns

GLP-1 RAs promote weight loss, enhancing satiety, reducing caloric intake, and delaying gastric emptying, which together reduce both the mechanical burden in intertriginous areas and systemic inflammation

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Chronic treatment should be with an oral B 12preparation

Comment Apoptosis is a form of genetically controlled programmed cell death. Microscopically in H&E-stained tissue sections, apoptosis appears as dense eosinophilic shrunken cell bodies with maintenance of membrane integrity, nuclear fragmentation and cytoplasmic budding, and without an inflammatory response