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Prepared for the Center for Food Safety and Applied Nutrition, Food and Drug Administration, Department of Health and Human Services, Washington, DC

Michels KA, Wactawski-Wende J, Mills JL, et al

Total flavonoids, extracted from Polygonum knotweed L, exert beneficial hepatoprotection against liver injury

We demonstrate the establishment of this workflow and how it is exploited to rapidly identify druggable targets and human approved compounds with antiviral efficacy in vitro and in vivo

Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer

This approach preserves the natural pulsatile rhythm of hormone release, which is generally considered a safer and more physiological method for addressing age-related decline