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Systemic symptoms : Fever, chills, malaise, or other systemic symptoms accompanying injection site reactions require medical assessment to rule out infection or hypersensitivity reactions

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It has been found that PPARGC1A is a transcriptional coactivator that drives the transformation of fast- to slow-twitch fibers via various biological pathways (e.g., glycolysis, the TCA cycle, and fatty acid -oxidation)