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Physiol Rev (1991) 71(1):151

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In future studies of VPA metabolites, it is important to use pharmacometabolomics together with pharmacogenomics to improve understanding of the biochemical pathways for the therapeutic and toxic metabolites formation, which may play an important role in individual variations in the phenotypes of the expected drug response to VPA, as well as in individual variations in the metabotypes associated with the risk of developing VPA-induced ADRs

Please note that this event will be conducted in Spanish