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For patients aged 12 to 17 years, the setmelanotide AUC and Cmax were both 26% higher as compared to patients aged greater than or equal to 18 years [ see Dosage and Administration (2.2, 2.3)]

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DOI: 10.1016/j.ejphar.2010.10.109

This approach has gained traction in patient communities, though clinical data specifically evaluating split dosing is limited

103 LiuS.LiL.ZhuangJ.LiM.YeL.ChenX.et al (2022)

GLP-1 medications are primarily used to treat type 2 diabetes and are also prescribed for chronic weight management in patients with obesity or related health risks