Biochem Soc Symp
GLP-1 medications, bariatric surgery, peptide therapy, and other medical weight loss treatments require evaluation by a licensed healthcare provider
Diabetes Care (2013) 36(3):498504
By addressing underlying issues such as inflammation and insulin resistance, these medications can transform lives
Clarifying these pathways may guide preventive or therapeutic strategies and improve patient quality of life
Eight major RCTs of GLP-1RAs have investigated the cardiovascular outcomes, including the ELIXA trial of lixisenatide (250), the EXSCEL trial of exenatide ER (251), the LEARDER trial of liraglutide (252), the SUSTAIN-6 trial of subcutaneous semaglutide (253), the HARMONY trial of albiglutide (228), the REWIND trial of dulaglutide (254), the PIONEER trial of oral semaglutide (255), and the SELECT trial of subcutaneous semaglutide (199)