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It plays a central role in supporting the body's healthy defense against oxidative stress and is a key component of phase II detoxification in the liver.1 Choline Choline plays an important role in the liver's natural protective mechanisms by supporting bile production and flow, as well as healthy fat metabolism.2 B Vitamins This group of vitamins, particularly B2, B6, B12, and folate, is essential for supporting healthy methylation processes, which are critical for detoxification

Kattan JD, Srinivasan KD, Zou ZM, Goldfarb J, Sampson HA, Li XM

The plasma half-life is estimated at 30-60 minutes, though biological effects on gene expression persist for hours to days

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Biochim Biophys Acta 1864:13151321 Lallement PA, Meux E, Gualberto JM, Dumarcay S, Favier F, Didierjean C, Saul F, Haouz A, Morel-Rouhier M, Gelhaye E, Rouhier N, Hecker A (2015) Glutathionyl-hydroquinone reductases from poplar are plastidial proteins that deglutathionylate both reduced and oxidized glutathionylated quinones