It was approved in the UK in 2023 for weight management in adults with: BMI 30 kg/m (obesity), or BMI 27 kg/m (overweight) with at least one weight-related condition The medication works through several mechanisms: Reduces hunger signals by acting on the brains appetite control centre Slows stomach emptying , creating longer-lasting fullness after meals Reduces food cravings , particularly for ultra-processed foods Improves blood sugar control by enhancing insulin function Clinical trials show that people taking Wegovy lose an average of 15% of their body weight after 68 weeks, compared to 2.4% with placebo
Additionally, they improve circulation and mobility, and even promote skin whitening
Timelines vary by person, goal, and protocol
Most stacks can be administered in the same injection if using the same delivery method, though some practitioners prefer separating them by several hours
No body composition endpoints have been tested in randomized controlled trials for either peptide
As I discuss below, you need to set yourself up for success by avoiding snacking and grazing in between meals
