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While tumor and germline genomic analyses have been widely investigated for use in other cancer treatment modalities, their clinical utility for radiotherapy has been less extensively explored

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SEAMARK: Randomized phase 2 study of pembrolizumab + encorafenib + cetuximab vs pembrolizumab alone for first-line treatment of BRAF V600Emutant microsatellite instabilityhigh (MSI-H)/mismatch repair deficient (dMMR) metastatic colorectal cancer (CRC)