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In the first Phase 3 trial of its once-daily oral GLP-1 pill in people with obesity, drugmaker Eli Lilly said Thursday that it helped people lower their weight by an average of 12% after 72 weeks

GLP-1 drugs for heart health Trulicity (dulaglutide) was approved in 2020 for individuals with type 2 diabetes, with or without a history of heart disease, to help reduce the risk of serious cardiovascular events, like heart attacks

In addition, the semaglutide injection (Ozempic) reduces the risk of stroke, heart attack, and death in adults with type 2 diabetes and heart disease

Chen Q, Miller LJ, and Dong M

The multiple sequence alignment of modified proteins to demonstrate the differences between the native and modified GLP-1 moieties in engineered fusion proteins is shown in Fig

Safe use of GLP-1 therapy hinges on close medical supervision and frequent kidney function tests