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They weren't quitting because the protocol wasn't workingthey were quitting because the treatment was unbearable i.e

Metabolic switching and ketogenesis Glycogen depletion : during fasting, glycogen stores in the liver are depleted, prompting the body to break down fat into free fatty acids and glycerol

CTLA4, a critical regulator of T-cell activation, is upregulated on CD4+ and CD8+ T cells in endometriosis, with elevated soluble CTLA4 (sCTLA4) in serum and peritoneal fluid of late-stage and infertility-associated cases

613,614 Astrocytes in AD animal models, as well as astrocytes differentiated from stem cells isolated from AD patients, are characterised by decreased energy metabolism, decreased glucose uptake and glucose consumption

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