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Deficiency is particularly common in elderly people, because the ability to absorb vitamin B12 can decrease with age ( Other people at risk of deficiency include those who have had intestinal surgery, including weight loss surgery

GHK-Cu modulates over 4,000 human genes

Supports genomic stability research: Telomere shortening can lead to chromosomal instability and altered gene expression

A 2025 review by Jozwiak and colleagues surveys the peptides multifunctionality and possible medical applications (PMC11859134), and is a useful map of what has and has not been established

Potential benefits of Tesamorelin: Reduced visceral fat Improved body composition Enhanced fat metabolism Possible improvement in metabolic markers Tesamorelin is FDA-approved for HIV-associated lipodystrophy but is increasingly discussed in body-composition medicine