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Importantly, most researchers now believe the therapeutic effects of MSCs occur primarily through paracrine signaling , meaning the cells release biologically active substances that influence surrounding tissues rather than directly replacing cells

David Putrino from the Icahn School of Medicine at Mount Sinai

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[2] Due to its potency and adverse reactions, oral minoxidil is used mainly for patients with severe, drug-resistant forms of hypertension

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The lack of independent replication or detailed data means these findings, while encouraging, are not considered high-quality evidence by todays standards