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After 48 h incubation at 27 C, the cells were collected by centrifugation and stored at 80 C until use

GLP-1s are primarily for treating type 2 diabetes, obesity, cardiovascular disease, and sleep apnea

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Early studies showed that sitagliptin induced decreased expression of pro-inflammatory proteins and decreased monocyte migration in apolipoprotein E-deficient mice may be attributed to GLP-1, which reduces monocyte migration and exerts anti-inflammatory effects by decreasing NFB [18, 19]

It is also used for detoxifying the liver and other cell-balancing purposes in various organs