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In the retatrutide phase 2 trial, at 12 mg over 48 weeks, every participant on the highest dose lost at least 5%, 93% lost at least 10%, and 83% lost at least 15%, with roughly two-thirds reaching 20% or more

Hormonal imbalances can make it difficult to lose weight and keep it off

Beyond pills or powders, you can also ramp up your fiber intake by changing what you put into your grocery cart

Reconciling the Mixed Picture Population differences: Clinical trials for obesity and diabetes often excluded patients with a history of major depression or other serious psychiatric issues

That last point is often missed

Readiness should be determined clinically