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In a randomized study where trimetazidine (35 mg/day) was prescribed for 4 days during elective coronary scaffold implantation, the trimetazidine group showed reduced IL-6 [166]

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Furthermore, in vivo experiments using MPTP-treated mice revealed that AST reversed behavioral deficits, preserved tyrosine hydroxylase (TH) expression, and reduced neuronal apoptosis, even in the presence of miR-7 knockdown

Metabolic changes in tamoxifen-resistant MCF-7 cell lines were manifested with the increase of glutathione, xanthine, and other metabolites involved in antioxidant pathways along with their dysfunctional genes' expression